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What is the fetal polycystic kidney disease?

  What is the fetal polycystic kidney disease?
 

  Fetal polycystic kidney disease is a genetic kidney disorder with autosomal recessive, which is a genetic abnormal about the kidney and biliary tract.

  Fetal polycystic kidney disease has two salient features in histopathological changes: the first one is spindle dilation of renal collecting duct, the second one is the uncompleted development of the portal vein area. The incidence of fetal polycystic kidney disease is about 1/20000.

  Children with fetal polycystic kidney disease can not live for more than a few hours after birth, the main cause of death is respiratory insufficiency. The causes for respiratory insufficiency includes: the lung grows incompletely, Significant kidney cysts caused transverse septum lifted, Pneumothorax and congestive heart failure. Death from kidney failure is rare.

  The survival babies always have hypertension, renal failure, portal hypertension and other symptoms. And due to kidney development and maturation, the FPKD babies birthing after 6 months will have a great improvement on the glomerular filtration rate, and then renal function decreased immediately. Some patients with fetal polycystic kidney disease in adolescence or early adulthood can enter the end stage renal failure.

  It can be seen that fetal polycystic kidney disease is a very serious disease, even if the child survived, they also have a malignant progression on the disease. Fetal polycystic kidney disease must be treated with the combination of traditional Chinese and Western medicine, which can achieve a certain effect.