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What are the symptoms of Henoch-Schonlein purpura nephritis?

  What are the symptoms of Henoch-Schonlein purpura nephritis?

  Henoch-Schonlein purpura nephritis refers to allergic purpura with necrotizing small vasculitis as the main pathological changes of the systemic disease caused by kidney damage. In addition to the clinical manifestations of Henoch-Schonlein purpura nephritis, arthralgia, abdominal pain, and blood, kidney involvement is mainly manifested in hematuria and proteinuria, and some patients with severe disease can cause impaired kidney function. Kidney involvement occurs more than a few days to several weeks after skin purpura.

  I. Renal external symptoms of Henoch-Schonlein purpura nephritis

  1, rash: the characteristics of allergic diesel crazy rash are bleeding and symmetrical distribution in the two lower limbs, to ankle, knee more see, also can be seen in the temple department and Upper limb, rash can repeatedly appear.

  2, joint symptoms: about half of the cases have wandering, multiple joint pain, part of the expression of joint swelling and activity is limited, often involving the knee, ankle and hand joints. Not left joint deformity, but can be repeated attacks.

  3, gastrointestinal symptoms: clinical manifestations of abdominal pain, paroxysmal colic, in children can be complicated intussusception, intestinal obstruction and intestinal perforation.

  4, other symptoms: liver, spleen, swollen lymph nodes, hemoptysis caused by pulmonary hemorrhage and so on.

  Renal manifestations of Henoch-Schonlein purpura nephritis

  1, nephritis syndrome type: continuous microscopic hematuria, often accompanied by mild proteinuria, edema, hypertension or slow renal function damage, this type of $number.

  2, repeated seizure of the naked eye hematuria type: This type often in the upper respiratory tract infection or intestinal infection during the naked eye hematuria, lasting 2-3 days into the microscopic hematuria, so repeated attack. Hematuria of the naked eye is often accompanied by proteinuria of different degrees, and the urine protein decreases or disappears after the naked eye hematuria disappears. Patients generally have no edema and high blood pressure, but often accompanied by lumbago, can be unilateral or bilateral, physical examination of the kidney area without significant percussion pain. This type is mostly found in children, about 20% of the disease.

  3, asymptomatic microscopic hematuria: Under the microscope, hematuria is often persistent, red blood cells in urine are mainly deformed red blood cells (more than 80%). Can be accompanied by mild proteinuria (24-hour urine protein quantitative 1g below), clinical asymptomatic, more in the physical examination found. This type is most visible, accounting for about 50%.

  4, nephrotic syndrome is characterized by a large number of proteinuria, low protein blood and microscopic hematuria, accounting for Henoch-Schonlein purpura nephritis 7%~16%. If accompanied by hypertension, renal function damage, the prognosis is poor.

  5, other types such as radical nephritis syndrome, acute renal failure. Account for about 5%. Less clinical, worse.

  Allergic purpura nephritis is often related to food, drugs, insect bites and other factors, found abnormal situation please seek medical advice, community doctors to strengthen publicity and education and health guidance, instruct patients to actively exercise, attention to prevent various predisposing factors.